Household Chemicals Negatively Affect Girls Thyroids

Household chemicals are negatively affecting young girls thyroids. In a first-of-its-kind study, researchers at Columbia University have found a link between exposure to phthalates and depressed thyroid function in young girls.

The study did show prenatal exposure to a metabolite of Di (2- ethylhexyl) phthalate was associated with elevated levels of FT4, a finding they say suggests phthalates affect thyroid function differently depending on the age of exposure.

“The thyroid acts as the master controller of brain development,” Pam Factor-Litvak, a professor of Epidemiology at the Mailman School, said in a press release. The thyroid disruptions we see in this study, although they fall within the normal range, could explain some of the cognitive problems we see in children exposed to phthalates and we are currently investigating that. As we know from lead, even small exposures can make a big difference.”

Here is the full study:



This article on the study of autism and it’s link to lower TSH levels in boys. Autism spectrum disorder (ASD) affects approximately 1 in 68 children in the USA. An ASD blood biomarker may enable early diagnosis and/or identification of new therapeutic targets.

The two proteins, thyroid-stimulating hormone (TSH) and interleukin-8 (IL-8), have been previously identified as putative biomarkers for ASD. TSH levels were significantly lower in ASD boys, whereas IL-8 levels were significantly elevated. The diagnostic accuracy for ASD based upon TSH or IL-8 levels alone varied from 74 to 76%, but using both proteins together, the diagnostic accuracy increased to 82%. In addition, TSH levels were negatively correlated with the Autism Diagnostic Observation Schedule subdomain scores.

You can read the full report here:


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